This past week I had the privilege of participating in a meeting hosted by the President’s Cancer Panel on the role of social media in improving cancer control and treatment. The goal was to give advice to the Panel on a planned series of meetings they will be convening to discuss the topic. It was the range and quality of the discussion that day that left me thinking about the broader topic of social media and how it could help improve cancer control going forward. [more]
I do not profess to be a social media expert. I do (obviously) engage in social media in a couple of ways, primarily through my blogs and Twitter (@DrLen), but I am not an addict. And notwithstanding the fact that social media has become a standard communication format for many folks, especially the younger generation, I still wonder how we are going to harness this revolution to improve what people know about cancer, what we can do with that information and how we can raise awareness about cancer-related issues such as new treatments, prevention, survivorship and clinical trials among many other topics.
The reality is that there hasn’t been much impact of social media … Continue reading →
Today marks a major step forward in cancer clinical trials and drug development with the launch of the Lung-MAP protocol to evaluate new treatments for squamous cell lung cancer, a common cancer which has proven resistant to the standard drugs currently available. In response to this genuine unmet need, Lung-MAP has been designed to move new therapies more quickly from the laboratory to the bedside of patients afflicted with this serious disease and few options available.
Many–including present company–have written about the need to improve this process. We are in a new era of cancer drug development, spearheaded by our ever increasing knowledge of cancer genes and the targets within those genes that can be used to disrupt the cancer cell on its inexorable road to proliferation and destruction. Getting those drugs speedily through development and clinical testing has been a real challenge. And, going forward, finding the patients with the “right” genomic signature who are candidates to receive these therapies is going to be difficult. In simple terms, we need to find the patients where they live and match them to these new drugs as quickly as possible. And that hopefully will translate into more and … Continue reading →
One hundred years.
That is a long time. And although thriving, remaining relevant and engaged for 100 years is a remarkable accomplishment for any organization, the American Cancer Society today takes pride not only in reflecting on the accomplishments of the last 100 years but also in our commitment to continue the fight, and make this century cancer’s last.
A lot will be written about the remarkable accomplishments of the Society over the past century. The American Cancer Society takes pride in the fact that it has been able to serve millions of people during that time. It has put its mark on numerous improvements in the science and treatment of cancer. We have made incredible strides in understanding cancer, what causes it and what influences it, including the role of tobacco and overweight/obesity. We have funded 46 Nobel Prize winners at some time during their careers, frequently when they needed a start to develop their theory which led to great discoveries. And we have funded numerous investigators who have made other important and lifesaving contributions to understanding cancer and reducing its burden.
But the list is not complete. There is still too much we don’t understand about cancer, its … Continue reading →
“You’ve come a long way baby!”
That slogan from decades ago now returns with a new meaning and a new vengeance, according to a study released today in the New England Journal of Medicine.
The report, co-authored by Michael Thun, the recently retired vice president emeritus of the American Cancer Society along with colleagues from several outstanding institutions in the United States, shows clearly and unfortunately that women who are smokers are now neck and neck with men smokers when it comes to the relative risk of dying compared to non-smokers, whether it is from all causes, lung cancer, chronic obstructive lung disease (emphysema), and cardiovascular diseases including heart disease and stroke. (See below for an explanation of relative risk)
In a somewhat unvarnished tone, the authors write, “This finding is new and confirms the prediction that, in relative terms, ‘women who smoke like men die like men.'” [more]
It wasn’t always that way. In the past, women who smoked were more likely to die than women who did not, but the increased risk was not as high as it was for men. But changes in how women smoke has changed that statistic over the last fifty years-and … Continue reading →
Lung cancer is the leading cause of cancer deaths in this country. In 2012, the American Cancer Society estimates that there were about 226,000 people newly diganosed with lung cancer, and 160,000 deaths. If there is good news here-and unfortunately there isn’t much good news when it comes to lung cancer-it is that deaths from this dreaded disease have been declining in men and women, since fewer people are smoking. But there is much we have to do to improve this picture.
That’s one of the reasons the American Cancer Society is releasing new guidelines on screening for lung cancer. After carefully reviewing the available research, the Society has concluded that there is good evidence that lung cancer screening saves lives by reducing deaths from lung cancer (20% in largest carefully controlled study) in people at high risk when the screening is done by experienced, high-volume lung cancer screening programs.
So who should be screened? Who is at high risk?
According to the guidelines, those for whom lung cancer screening with low-dose chest CT scans are appropriate are people who are between the ages of 55 and 74 and who have smoked 30 pack years (a pack year is one pack of … Continue reading →
The positive news continues: cancer death rates have continued to fall in the United States, for men and women, maintaining a trend that began in the early 1990’s. That’s the essence of a report released today by the American Cancer Society, the National Cancer Institute, the Centers for Disease Control and Prevention and the North American Association of Central Cancer Registries in the Journal of the National Cancer Institute.
The report, titled in part “Annual Report to the Nation on the Status of Cancer, 1975-2009” also features a special section on the burden and trends in Human Papilloma virus (HPV) associated cancers and HPV vaccination coverage levels. Unlike the continuing decline in cancer deaths in the United States, we could be doing a much better job of getting young folks vaccinated against HPV and reducing the incidence and death rates from several HPV-associated cancers, according to the authors of the report and an editorial that accompanied the report.
This report comes out every year. It is a summation of what we know about the trends in incidence rates for the most common cancers in the United States among both men and women as well as the trends … Continue reading →
Now that we are saying goodbye to the pink of October as we move onward from breast cancer awareness month, let us welcome the month of November, when we will shift our attention to lung cancer.
An article I read this past week posted on “Fair Warning” highlighted these issues, using breast cancer and lung cancer as a frame of reference. It carefully and in my personal opinion very professionally looked at the differences. Not casting blame, not failing to report both sides of the story, the author concisely pointed out how the way we relate to these two cancers is so fundamentally different.
In October we are awash in pink. Sometimes it seems the whole world is “pinked.” Breast cancer is a passionate and compassionate topic, one that touches so many aspects of our sensitivities and sensibilities. It is a disease which frightens many women. It is a disease worthy of our efforts to find a preventive strategy that is acceptable and a treatment that will provide a cure. It is a disease which in our minds is almost always curable, if only we find it early. And-please keep this in mind-it is a disease where the perception … Continue reading →
The “Annual Report to the Nation on the Status of Cancer” was released this afternoon as has been the case every year since the first report was issued in 1998. And, like many of the reports previously, we are fortunate to continue to see declines in the rates of deaths for many cancers along with a decrease in the frequency of some cancers.
However, the news is not all good.
Unfortunately, the incidence of some cancers continues to increase. And, as explained very clearly in this excellent report, this nation continues to suffer from an epidemic of overweight, obesity and physical activity that the authors suggest-but don’t actually say-has the potential to overcome the favorable impact of declining smoking and tobacco use on cancer incidence and deaths. The implication is clear that if we don’t do something-and do something quickly-to reverse the trend we will see incidence and deaths from certain cancers continue to increase in the future.
And I would stress the point that it is no longer just being oversized that increases your risk of cancer, but also sitting all day on the job (like I am doing right now) as another factor that plays … Continue reading →
I had the opportunity yesterday to attend the event marking the release of the 31st Surgeon General’s report on tobacco and smoking.
What struck me about this report-which focuses on tobacco use in youth and young adults–is that although we have made progress in the tobacco wars, we presently seem to be in a holding action. We are not making advances in reducing the incidence of smoking and use of smokeless tobacco products, although we are all well aware of their risks and harms.
The fundamental question remains: Although we have a pretty good idea of what works, when are we going to start reinvigorating our efforts to reduce the use of these killer products among our children?
As I have said many times before, tobacco is the one product readily and legally available in the United States that when used as intended will kill half the people who use it. 443,000 deaths a year, 1200 a day, $96 billion each year in direct medical costs and $97 billion in lost productivity. Those, my friends, are big numbers. And they are not just numbers: they are people. They are the people we love, the people we … Continue reading →
Welcome to the New Year!
And as has been the case for many years in the past, the American Cancer Society takes the New Year opportunity of providing the nation with the latest estimates of cancer incidence and deaths, along with a measure of how well we are doing in reducing the burden of cancer in the United States.
The data is contained in two reports released today by the Society: the consumer oriented Cancer Facts and Figures 2012 and the more scientifically directed Cancer Statistics 2012. Both are available online.
It is never “good news” to realize that the burden of cancer in this country is immense. And with the country gaining in population and age, the extent of that burden is inevitably going to increase. But this year’s report does contain some welcome information, namely that cancer death rates have declined in men and women of every racial/ethnic group over the past 10 years, with the sole (and unfortunate) exception of American Indians/Alaska Natives. In addition, the Society now estimates that a bit more than one million cancer deaths (1,024,400 to be exact) have been avoided since 1991-1992.
That one million number is actually … Continue reading →